Centrus Energy has announced multiple partnerships this week aiming to increase its fuel capacities and activities at its uranium enrichment facility in Piketon, Ohio.
Centrus and Oklo agreed on Monday to seek a joint venture focused on deconversion services for high-assay low-enriched uranium (HALEU) and advancing fuel-cycle technologies in Ohio. The company then agreed to partner with Palantir Technologies Thursday to use artificial intelligence (AI) tools to support its expansion at the Piketon site.
For the possible joint venture, Centrus and Oklo companies announced in a press release that the activities for it will take place at Centrus’ Piketon uranium enrichment facility site in Pike County, Ohio and co-located at Oklo’s planned 1,200-megawatt power campus. Oklo’s planned campus comes as a part of an agreement from January with Meta to power its data centers.
The joint venture aims to enable an integrated pairing of uranium enrichment and deconversion to improve efficiency and costs through co-location, according to the release.
Uranium deconversion is the chemical extraction of the fluoride from depleted uranium hexafluoride, a byproduct of enrichment, into more stable uranium oxides. This occurs before it can be fabricated into fuel for nuclear reactors.
The two companies will also look to expand domestic advanced nuclear fuel capacity to serve Oklo’s needs, such as reactor fuel, and other domestic reactor deployments.
Centrus and Oklo said they plan to explore opportunities for coordination of regulatory research and development activities. These activities include joint engagement with federal agencies to propose solutions that support co-location of deconversion and enrichment services, the companies said.
For the Palantir partnership, Centrus said in its press release it will leverage Palantir’s Foundry and Artificial Intelligence Platform to use AI to optimize project controls, supply chain management and regulatory compliance. The system will also be used to integrate various systems across classified and unclassified environments, Centrus added.
Centrus said the partnership between Palantir started in late January, but the companies have already identified nearly $300 million in potential cost savings. The companies said additional improvements have been noted and will look to reduce manufacturing lead times and bring new uranium enrichment capacity at a sooner date.
Centrus announced plans for a multi-billion-dollar expansion of its Piketon uranium enrichment plant September 2025 and began manufacturing centrifuges at its Oak Ridge, Tenn. facility for the expansion in December 2025.
Since the announcement of expanding its Piketon uranium enrichment facility, Centrus has entered into several partnerships to assist with its expansion plans. In February, Fluor agreed to be the engineering, procurement and construction contractor for the project.
Amir Vexler, Centrus president and CEO, said during Centrus’ fourth quarter earnings call in February that the company has a list of partnerships that it will announce over time.